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    • X Chromosome Inactivation
    • Allelic Imbalance
    • cis vs. trans Regulation
    • DNA Methylation
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Xu Wang's Research Skills
  • Lab skills                                                                                                                            
    Sample collection, DNA and RNA extraction, agarose gel, PCR primer design, PCR, RT-PCR, qPCR, 5’ and 3’-RACE, restriction enzyme analysis, STRs scanning, Sanger sequencing, Bisulfite-sequencing, Pyrosequencing, Pyro-Mark, Illumina library preparation for gDNA-seq, RNA-seq, WGBS-seq and ChIP-seq, Agilent SNP-typing array design and hybridization, NimbleGen seq-cap array hybridization.
  • Computational/Statistics Skills
  • ·  Unix shell scripting, Linux/Unix system administration, cluster computing, C and Perl programming, MySQL database applications;
    ·  Statistical software: R, JMP and SAS.

  • Bioinformatic Skills
    ·   Nextgen sequencing data analysis (Illumina, SOLiD, 454);
    ·   Microarray primer design (for expression, SNP-typing and seq capture chip);
    ·   Genetic linkage analysis and segregation analysis;
    ·   Phylogenetic tree construction;
    ·   Population genetic analysis and QTL mapping.
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